Researchers at the Technical University of Munich have discovered that the success of liver regeneration following surgery is largely dependent on gut bacteria. A healthy microbiome consisting of various bacteria is necessary for short-chain fatty acids (SCFAs) to be produced. These SCFAs are required by liver cells to grow and divide, and if there is a deficiency in SCFAs, liver regeneration is hindered. The researchers demonstrated this by conducting experiments on mice with disrupted microbiomes, which showed delayed formation of new liver cells. However, treating the mice with a “microbiome starter set” stimulated liver regeneration. In addition to potentially influencing patient selection for liver surgery, the study offers insights into the complex role of gut bacteria in our bodies.
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Gut Bacteria Play Key Role in Liver Regeneration, Study Finds
GIbiome 